Skeletal muscle gene expression profiles in 20–29 year old and 65–71 year old women
S Welle, AI Brooks, JM Delehanty, N Needler… - Experimental …, 2004 - Elsevier
Gene expression profiling may provide leads for investigations of the molecular basis of
functional declines associated with aging. In this study, high-density oligonucleotide arrays
were used to probe the patterns of gene expression in skeletal muscle of seven young
women (20–29 years old) and eight healthy older women (65–71 years old). The older
subjects had reduced muscle mass, strength, and peak oxygen consumption relative to
young women. There were∼ 1000 probe sets that suggested differential gene expression in …
functional declines associated with aging. In this study, high-density oligonucleotide arrays
were used to probe the patterns of gene expression in skeletal muscle of seven young
women (20–29 years old) and eight healthy older women (65–71 years old). The older
subjects had reduced muscle mass, strength, and peak oxygen consumption relative to
young women. There were∼ 1000 probe sets that suggested differential gene expression in …
