Appropriate vessel development and its coordinated function is essential for proper
embryogenesis and homeostasis in the adult. Defects in vessels cause birth defects and are
an important etiology of diseases such as cardiovascular disease, tumor and diabetes
retinopathy. The accumulative data indicate that ETV2, an ETS transcription factor, performs
a potent and indispensable function in mediating vessel development. This review
discusses the recent progress of the study of ETV2 with special focus on its regulatory …